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Gloria A. Gronowicz, Ph.D.

Gloria A. Gronowicz, Ph.D.

Professor
Department of Surgery


Education

  • Columbia University
    New York, NY
    Ph.D.
  • University of Chicago
    Chicago, IL
    Postdoctoral Fellowship

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Research Interests

Since her training is in molecular and cell biology, Dr. Gloria A. Gronowicz has combined her interest in energy medicine with cell biology techniques. The goal of her laboratory is to understand the effect of therapeutic touch on the growth and differentiation of cells. Her laboratory has studied normal cells isolated from patients’ tendon, bone and skin, and compared their responses to those from transformed cell lines, in particular derived from osteosarcomas. The mechanism for the effects that they have found on these cells, is being investigated, in particular cell signaling pathways, integrins, and the synthesis of extracellular matrix proteins. They were funded as an Exploratory Program Grant for Frontier Grant by the National Center of Complementary and Alternative Medicine at the National Institutes of Health in Washington, D.C.

In addition, her laboratory is involved in tissue engineering, and studies the mechanism for biocompatibility of materials in humans. They devise novel biomaterials that will augment bone formation, in particular in human aging and for patients with debilitating musculoskeletal diseases. In addition, they are investigating the cell biology of glucocorticoid-induced osteoporosis.

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Educational Interests

Dr. Gloria A. Gronowicz teaches medical students evidence-based complementary and alternative medicine (CAM) at the University of Connecticut Health Center as part of the third year program. This also involves hands-on demonstrations of some CAM modalities. With a team of faculty interested in CAM, she has participated in several CAM fairs, seminars and programs for the Health Center and greater Hartford community. She is a member of the Programs in Complementary and Integrative Medicine that meets on a monthly basis. Finally, she is also a member of the Research Working Group for the Consortium of Academic Health Centers for Integrative Medicine.

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Abstracts

Jhaveri, A.P., M.B. McCarthy, Y Wang and G. Gronowicz, 2005 Therapeutic Touch affects proliferation and bone formation in vitro. J. Bone Mineral Res 19;S402.

Gronowicz, G. and A. Jhaveri, 2005. Therapeutic Touch Stimulates Proliferation of Human Osteoblasts, Fibroblasts, and Tenocytes. Transactions of the “International Society for the Study of Subtle Energy and Energy Medicine”.

Gronowicz, G. MB McCarthy, and A. Jhaveri, 2006. Therapeutic Touch inhibits bone formation of human osteosarcoma cells in vitro. Transactions of the “North American Conference on Complementary and Integrative Medicine”, Edmonton, Canada.

Gronowicz, G., 2007 “Therapeutic Touch Inhibits the Growth and Bone-Forming Ability of Human Osteosarcoma-Derived Cells in Culture’ for the Society for Integrative Oncology, San Francisco, CA.

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Recent Publications (From a List of 88)

Zhang, H. and G. Gronowicz, 2005. Transforming Growth Factor-Beta 1(TGF-1) enhances age-dependent decrease in mineralization in primary human osteoblast/implant cultures. J. Biomed Biomat Res. 75A:98-105.62.

Pantschenko, A.G., W. Zhang, M. Nahounou, M.B. McCarthy, M.L. Stover, A.C. Lichtler, S. H. Clark and G. Gronowicz, 2005 The effect of osteoblast targeted expression of Bcl-2 in bone: differential response in male and female mice. J. Bone Mineral Res 20:1414-142.

Kardestuncer, T., M.B. McCarthy, V. Karageorgiou, D. Kaplan and G. Gronowicz, 2006. RGD-tethered silk substrates stimulate the differentiation of human tendon cells. Clin. Orthopaedic Rel. Res. 448:234-239.

Gronowicz, G. and A. Jhaveri, 2006. The cell biology of energy medicine: a human osteoblast-based study on Therapeutic Touch. Elements 4: 6-8.

Zhang, W., A. Pantschenko, M.B. McCarthy, and G. Gronowicz, 2007. Bone targeted overexpression of Bcl-2 increases osteoblast adhesion, differentiation, and inhibits mineralization. Calcif Tissue Int. 80:111-122.

Lin, S, F.S. Barnes, M.R. Cho, J. Fox, C. Fransomeno, D.E. Golan, G. A. Gronowicz, R.G. Jahn, J.P. Jones, K.H. Probram, S.W. Porges, P.E. Rapp, B. Rubik, G.E. Schwartz, W.A. Tiller, G. Yount and M.C. Ziskin, 2007. A Think Tank Working Group Meeting on Biofield Energy Medicine”, proceedings from the March 29-31, 2006 meeting at NCCAM in Bethesda, MD.

Liu, F., S-K. Lee, D.J. Adams, G. A. Gronowicz and B.E. Kream, 2007 CREM deficiency in mice blunts the anabolic effect of intermittent parathyroid hormone treatment on bone mass acquisition. Bone 40:1135-1143.

Gronowicz, G., 2007. ‘Therapeutic Touch affects osteoblast proliferation and bone formation in cell culture’ for the journal “Connection” of Nurse Healers-Professional Associates International, XXVII (7):1-3.

Sagomonyants, K., M. Jarman-Smith, J. Devine and G. Gronowicz, 2008. The Response of Human Osteoblasts to Polyetheretherketone (PEEK) Substrates. Biomaterials, 29(11):1563-72.

Gronowicz, G, A. Jhaveri, L.W. Clarke, M.S. Aronow, T.H. Smith, 2008. Therapeutic Touch stimulates the proliferation of human cells in culture. J Alternative Complementary Med 14(3):233-239.

Jhaveri, A., Y. Wang, M.-B. McCarthy and G.A. Gronowicz, 2008. Therapeutic Touch affects proliferation and bone formation of human osteoblasts in vitro. In press, J Orthop. Res.

Gronowicz, G, and A. Jhaveri, 2008. The effect of Therapeutic Touch on the growth and differentiation of osteosarcoma-derived cells. Manuscript in preparation.


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Contact Information

Gloria A. Gronowicz, Ph.D.
Professor

Department of Surgery
University of Connecticut Health Center
263 Farmington Avenue
Farmington, CT 06030

Phone: 860-679-3842
Fax: 860-679-2103
Email: gronowicz@nso1.uchc.edu

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